Rapid-Acting, As-Needed Medications for Trigeminally-Mediated Pain

Dr. Wolfgang Liedtke is an Executive with Regeneron Pharmaceuticals (Tarrytown, NY) in Genetic Medicines in their Global Clinical Development Unit, and member of their Scientific Council where he is Chair of Neurology, Psychiatry, Pain Medicine and Sensory Systems. Prior to joining Regeneron in 2021, he was a tenured professor at Duke University for 17 year. He conducted basic neuroscience pain research and co-founded the Duke University pain research group. He also founded two Duke clinics dedicated to pain medicine, one in neurology, one in anesthesiology, providing science-based yet empathetic clinical care to patients suffering from head face pain, generally refractory pain and pain in the context of complex comorbidities.

He was clinically trained in neurology and psychiatry in his native Germany and in neuropathology in New York City, where he conducted neuropathology and molecular genetics research (Albert Einstein College of Medicine; The Rockefeller University), after coming to the US in 1994. Dr. Liedtke is a member of the FPA Medical Advisory Board, an elected member of the American Clinical and Climatological Association (Little Rock AR), a faculty member of the NYU Pain Research Center, Adjunct Professor of Neurology at Duke, and Adjunct Professor of Dentistry at NYU. 

Dr. Liedtke has contributed a chapter on facial pain medications in the forthcoming second edition of our book, titled Facial Pain: A 21st Century Guide, Book II. In this chapter, he discusses various medications that can be used to manage chronic facial pain under the guidance of a physician, depending on the severity of the pain.  

Dr. Liedtke categorizes these medications into three types:  

  • As-needed/rescue medications  
  • Baseline medications for continuous management  
  • Injectables for maintenance management 

Click the button below to download the chart of as-needed/rescue medications. These medications address the question: What can you do when the becomes intolerable?

Facial Pain: A 21st Century Guide, Book II will be published later this year. To purchase the first edition of the book, visit https://www.facepain.org/understanding-facial-pain/buy-the-book/.

Disclaimer: The information contained in this list is not intended to be individual medical advice, diagnosis, or treatment or to induce the reader to seek care with any specific physician. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment, before undertaking a new health care treatment, and never disregard professional medical advice or delay in seeking it because of something you have read in this list.

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By filling out the form below, you will receive a free FPA Patient Guide and periodic updates on the management and treatment of facial pain conditions. We do not share this information with any outside sources.